NFC West
San Francisco 49ers
13-42022 Season
Points For
450
Points Against
277
Differential
+173
2022 Schedule
| Wk | Date | Opponent | Result | Score | Venue |
|---|---|---|---|---|---|
| 1 | Sep 11, 2022 | @ Chicago Bears | L | 10-19 | Soldier Field |
| 2 | Sep 18, 2022 |  Seattle Seahawks | W | 27-7 | Levi's Stadium |
| 3 | Sep 25, 2022 | @ Denver Broncos | L | 10-11 | Empower Field at Mile High |
| 4 | Oct 3, 2022 |  Los Angeles Rams | W | 24-9 | Levi's Stadium |
| 5 | Oct 9, 2022 | @ Carolina Panthers | W | 37-15 | Bank of America Stadium |
| 6 | Oct 16, 2022 | @ Atlanta Falcons | L | 14-28 | Mercedes-Benz Stadium |
| 7 | Oct 23, 2022 |  Kansas City Chiefs | L | 23-44 | Levi's Stadium |
| 8 | Oct 30, 2022 | @Los Angeles Rams | W | 31-14 | SoFi Stadium |
| 10 | Nov 13, 2022 |  Los Angeles Chargers | W | 22-16 | Levi's Stadium |
| 11 | Nov 21, 2022 | @ Arizona Cardinals | W | 38-10 | Azteca Stadium |
| 12 | Nov 27, 2022 |  New Orleans Saints | W | 13-0 | Levi's Stadium |
| 13 | Dec 4, 2022 |  Miami Dolphins | W | 33-17 | Levi's Stadium |
| 14 | Dec 11, 2022 |  Tampa Bay Buccaneers | W | 35-7 | Levi's Stadium |
| 15 | Dec 15, 2022 | @Seattle Seahawks | W | 21-13 | Lumen Field |
| 16 | Dec 24, 2022 |  Washington Commanders | W | 37-20 | Levi's Stadium |
| 17 | Jan 1, 2023 | @ Las Vegas Raiders | W | 37-34 | Allegiant Stadium |
| 18 | Jan 8, 2023 | Arizona Cardinals | W | 38-13 | Levi's Stadium |
| 19WC | Jan 14, 2023 | Seattle Seahawks | W | 41-23 | Levi's Stadium |
| 20DIV | Jan 22, 2023 |  Dallas Cowboys | W | 19-12 | Levi's Stadium |
| 21CON | Jan 29, 2023 | @ Philadelphia Eagles | L | 7-31 | Lincoln Financial Field |