NFC North
Detroit Lions
3-13-12021 Season
Points For
325
Points Against
467
Differential
-142
2021 Schedule
| Wk | Date | Opponent | Result | Score | Venue |
|---|---|---|---|---|---|
| 1 | Sep 12, 2021 |  San Francisco 49ers | L | 33-41 | Ford Field |
| 2 | Sep 20, 2021 | @ Green Bay Packers | L | 17-35 | Lambeau Field |
| 3 | Sep 26, 2021 |  Baltimore Ravens | L | 17-19 | Ford Field |
| 4 | Oct 3, 2021 | @ Chicago Bears | L | 14-24 | Soldier Field |
| 5 | Oct 10, 2021 | @ Minnesota Vikings | L | 17-19 | U.S. Bank Stadium |
| 6 | Oct 17, 2021 |  Cincinnati Bengals | L | 11-34 | Ford Field |
| 7 | Oct 24, 2021 | @ Los Angeles Rams | L | 19-28 | SoFi Stadium |
| 8 | Oct 31, 2021 |  Philadelphia Eagles | L | 6-44 | Ford Field |
| 10 | Nov 14, 2021 | @ Pittsburgh Steelers | T | 16-16 | Heinz Field |
| 11 | Nov 21, 2021 | @ Cleveland Browns | L | 10-13 | FirstEnergy Stadium |
| 12 | Nov 25, 2021 | Chicago Bears | L | 14-16 | Ford Field |
| 13 | Dec 5, 2021 | Minnesota Vikings | W | 29-27 | Ford Field |
| 14 | Dec 12, 2021 | @ Denver Broncos | L | 10-38 | Empower Field at Mile High |
| 15 | Dec 19, 2021 |  Arizona Cardinals | W | 30-12 | Ford Field |
| 16 | Dec 26, 2021 | @ Atlanta Falcons | L | 16-20 | Mercedes-Benz Stadium |
| 17 | Jan 2, 2022 | @ Seattle Seahawks | L | 29-51 | Lumen Field |
| 18 | Jan 9, 2022 | Green Bay Packers | W | 37-30 | Ford Field |